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Paper-filtered coffee increases cholesterol and inflammation biomarkers independent of roasting degree: A clinical trial.

Authors :
Corrêa, Telma A. F.
Rogero, Marcelo M.
Mioto, Bruno M.
Tarasoutchi, Daniela
Tuda, Vera L.
César, Luiz A. M.
Torres, Elizabeth A. F. S.
Source :
Nutrition. Jul/Aug2013, Vol. 29 Issue 7/8, p977-981. 5p.
Publication Year :
2013

Abstract

Objective: The aim of this study was to compare the effects of medium light roast (MLR) and medium roast (MR) paper-filtered coffee on cardiovascular risk factors in healthy volunteers. Methods: This randomized crossover trial compared the effects of consuming three or four cups (150 mL) of MLR or MR coffee per day for 4 wk in 20 healthy volunteers. Plasma lipids, lipoprotein( a) (Lp[a]), total homocysteine, and endothelial dysfunction-related inflammation biomarkers, serum glycemic biomarkers, and blood pressure were measured at baseline and after each intervention. Results: Both roasts increased plasma total cholesterol, low-density lipoprotein-cholesterol, and soluble vascular cell adhesion molecule-1 (sVCAM-1) concentrations (10%, 12%, and 18% for MLR; 12%, 14%, and 14% for MR, respectively) (P < 0.05). MR also increased high-density lipoporteincholesterol concentration by 7% (P = 0.003). Plasma fibrinogen concentration increased 8% after MR intake (P = 0.01), and soluble E-selectin increased 12% after MLR intake (P = 0.02). No changes were observed for Lp(a), total homocysteine, glycemic biomarkers, and blood pressure. Conclusion: Moderate paper-filtered coffee consumption may have an undesirable effect on plasma cholesterol and inflammation biomarkers in healthy individuals regardless of its antioxidant content. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
08999007
Volume :
29
Issue :
7/8
Database :
Academic Search Index
Journal :
Nutrition
Publication Type :
Academic Journal
Accession number :
88216025
Full Text :
https://doi.org/10.1016/j.nut.2013.01.003