Back to Search
Start Over
New classification of oesophageal and gastric carcinomas derived from changing patterns in epidemiology.
- Source :
-
British Journal of Cancer . 5/15/99, Vol. 80 Issue 5/6, p834. 9p. - Publication Year :
- 1999
-
Abstract
- The current ICD-O classification of carcinomas of the oesophagus and stomach causes epidemiological and clinical confusion. This study compares the epidemiological and clinical features of each subtype and subsite of adenocarcinomas of the oesophagus and stomach, to assess requirements for a new classification of these carcinomas. Data were extracted with appropriate validity checks on all cases of oesophageal and gastric carcinomas identified throughout the period 1974-1993 by the Merseyside and Cheshire Cancer Registry, which covers a population of 2.5 million. The incidence of adenocarcinomas of the lower oesophagus and cardia trebled in males, and doubled in females, whereas adenocarcinoma of the subcardia region of the stomach declined in both sexes. Adenocarcinomas of the lower oesophagus and of the cardia were similar for median age at diagnosis, male to female ratio, percentage of patients who smoked and survival; both were significantly different from carcinomas of the subcardia in these respects. These data imply that adenocarcinomas of the lower oesophagus and cardia are the same disease. A new subsite classification of oesophageal and gastric carcinomas is proposed that includes the gastro-oesophageal junction as a distinct subsite, to facilitate surveillance, management and research. [ABSTRACT FROM AUTHOR]
- Subjects :
- *STOMACH cancer
*EPIDEMIOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 00070920
- Volume :
- 80
- Issue :
- 5/6
- Database :
- Academic Search Index
- Journal :
- British Journal of Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 8878254
- Full Text :
- https://doi.org/10.1038/sj.bjc.6690429