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Characterization of AntB, a Promiscuous Acyltransferase Involved in Antimycin Biosynthesis.
- Source :
-
Organic Letters . Vol. 15 Issue 13, p3396-3399. 4p. - Publication Year :
- 2013
-
Abstract
- The in vivoand in vitrocharacterization of AntB, a dedicated acyltransferase encoded in the antimycin biosynthetic gene cluster, which catalyzes the C-8 acyloxy formation is reported. It is demonstrated that AntB has broad substrate specificity toward both the acyl substrate and the acyl carrier and produces more antimycin analogues with varying C-8 acyloxy moieties. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 15
- Issue :
- 13
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 88918867
- Full Text :
- https://doi.org/10.1021/ol4014365