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Alarin but not its alternative-splicing form, GALP (Galanin-like peptide) has antimicrobial activity.

Authors :
Wada, Akihiro
Wong, Pooi-Fong
Hojo, Hironobu
Hasegawa, Makoto
Ichinose, Akitoyo
Llanes, Rafael
Kubo, Yoshinao
Senba, Masachika
Ichinose, Yoshio
Source :
Biochemical & Biophysical Research Communications. May2013, Vol. 434 Issue 2, p223-227. 5p.
Publication Year :
2013

Abstract

Highlights: • Alarin inhibits the growth of E. coli but not S. aureus. • Alarin’s potency is comparable to LL-37 in inhibiting the growth of E. coli. • Alarin can cause bacterial membrane blebbing. • Alalin does not induce hemolysis on erythrocytes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0006291X
Volume :
434
Issue :
2
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
88983678
Full Text :
https://doi.org/10.1016/j.bbrc.2013.03.045