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BCR/ABL genes and leukemic phenotype: from molecular mechanisms to clinical correlations.

Authors :
Pane, Fabrizio
Intrieri, Mariano
Quintarelli, Concetta
Izzo, Barbara
Muccioli, Giada Casadei
Salvatore, Francesco
Source :
Oncogene. 12/9/2002 Review, Vol. 21 Issue 56, p8652. 16p. 2 Diagrams, 4 Charts.
Publication Year :
2002

Abstract

Offers insight into the different transforming power of the three hybrid BCR/ABL proteins. History of the hybrid BCR/ABL gene; Molecular structure of BCR/ABL genes; Correlation of BCR breakpoint positions with leukemic phenotype; Structure and biological features of proteins, ABL, BCR and of the various BCR/ABL fusion proteins.

Details

Language :
English
ISSN :
09509232
Volume :
21
Issue :
56
Database :
Academic Search Index
Journal :
Oncogene
Publication Type :
Academic Journal
Accession number :
8907009
Full Text :
https://doi.org/10.1038/sj.onc.1206094