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Fenofibrate ameliorates cardiac hypertrophy by activation of peroxisome proliferator-activated receptor-α partly via preventing p65-NFκB binding to NFATc4.
- Source :
-
Molecular & Cellular Endocrinology . May2013, Vol. 370 Issue 1/2, p103-112. 10p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Fenofibrate ameliorates cardiac hypertrophy in vivo and in vitro. [•] The interaction between p65-NFκB and NFATc4 regulates cardiac hypertrophy. [•] Fenofibrate attenuates cardiac hypertrophy via activating PPAR-α and thereby preventing the association of p65-NFκB with NFATc4. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 03037207
- Volume :
- 370
- Issue :
- 1/2
- Database :
- Academic Search Index
- Journal :
- Molecular & Cellular Endocrinology
- Publication Type :
- Academic Journal
- Accession number :
- 89070750
- Full Text :
- https://doi.org/10.1016/j.mce.2013.03.006