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Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses.
- Source :
-
Antiviral Research . Jun2013, Vol. 98 Issue 3, p432-440. 9p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Three imino sugars (IHVR11029, 17028 and 19029), were identified through SAR study of 120 derivatives. [•] These three imino sugars demonstrated broad antiviral activities against HFVs in vitro, and in vivo. [•] All three compounds inhibited ER α-glucosidases in vitro and in vivo. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 01663542
- Volume :
- 98
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Antiviral Research
- Publication Type :
- Academic Journal
- Accession number :
- 89103449
- Full Text :
- https://doi.org/10.1016/j.antiviral.2013.03.023