Multi-microarray identifies lower AQP9 expression in adjuvant chemotherapy nonresponders with stage III colorectal cancer.

Highlights: [•] Gene expression and miRNA arrays of nonresponders’ and responders’ fresh-frozen tissues were compared. [•] We find 59 genes and 17 miRNAs differentially expressed by at least two folds. [•] Expression of AQP9, SATB2, and WIF1 are lower in the nonresponders and modulated by differentially expressed miRNAs. [•] RT-PCR validates lower expression of AQP9, but not the other two genes, in nonresponders. [ABSTRACT FROM AUTHOR]