Total intravenous anesthesia affecting spike sources of magnetoencephalography in pediatric epilepsy patients: Focal seizures vs. non-focal seizures.

Highlights: [•] Reduction of MEG spike sources occurred in patients with focal seizure under TIVA. [•] Diffuse/generalized spikes in non-focal seizures resist the inhibitory effect by TIVA. [•] Propofol may decrease focal spikes in the epileptic cortex in focal seizures. [•] Cortical hyperexcitability in non-focal seizure group would be strong or extensive. [ABSTRACT FROM AUTHOR]