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Leptin and ghrelin prevent hippocampal dysfunction induced by Aβ oligomers.
- Source :
-
Neuroscience . Jun2013, Vol. 241, p41-51. 11p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Leptin and ghrelin protect hippocampal neurons from Aβ oligomers-induced toxicity. [•] Leptin and ghrelin prevent oxidative stress and mitochondrial dysfunction. [•] Leptin and ghrelin revert GSK3β activation induced by Aβ oligomers. [•] Neuroprotection by leptin and ghrelin occurs in a receptor-mediated manner. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03064522
- Volume :
- 241
- Database :
- Academic Search Index
- Journal :
- Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 89217818
- Full Text :
- https://doi.org/10.1016/j.neuroscience.2013.02.062