Enhanced excitability of guinea pig ileum myenteric AH neurons during and following recovery from chemical colitis.

Highlights: [•] Intrinsic primary afferent neurons of the ileum are hyperexcitable during colitis. [•] Excitability of ileum myenteric AH neurons persists after colitis has resolved. [•] There are no changes in fast synaptic transmission in the ileum during colitis. [•] An early transient reduction in small bowel transit is restored during colitis. [•] Neither reduced transit nor restoration coincide with changes in AH excitability. [ABSTRACT FROM AUTHOR]