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On-column refolding of bone morphogenetic protein-2 using cation exchange resin.
- Source :
-
Protein Expression & Purification . Aug2013, Vol. 90 Issue 2, p135-140. 6p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] A novel BMP-2 dimer refolding procedure using weak cation exchange resin. [•] Weakly bound monomer dissociates from resin but refolded dimer rebinds strongly. [•] Simultaneous refolding and purification using on-column ion exchange chromatography. [•] Potential applications on refolding of other dimer proteins such as TGF-β and VEGF. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 10465928
- Volume :
- 90
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Protein Expression & Purification
- Publication Type :
- Academic Journal
- Accession number :
- 89343373
- Full Text :
- https://doi.org/10.1016/j.pep.2013.05.008