Distinct functional brain regional integration of Casp3, Ascl1 and S100a6 gene expression in spatial memory.

Highlights: [•] In the water maze, spatial memory was formed in Wister rats after 4-day training. [•] PCR revealed specific brain regional profiles of Ascl1, S100a6 and Casp3 expression. [•] These genes were associated with coupled neurogenesis/apoptosis/neuroplasticity. [•] An intra-structural prefrontal cortex/cerebellum correlation was shown to Casp3. [•] Hippocampal, prefrontal cortical and cerebellar integration was validated in memory. [ABSTRACT FROM AUTHOR]