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Results of treatment for pT1/pT2 carcinomas of the floor of mouth.
- Source :
-
Acta Oto-Laryngologica . Sep2013, Vol. 133 Issue 9, p1000-1005. 6p. - Publication Year :
- 2013
-
Abstract
- Conclusion: In pT2 floor of mouth cancer (FOMC), a standardized neck dissection (ND) should be carried out, due to the high risk of occult metastases. In cases of pT1 carcinomas with a clinically negative neck using high imaging standards and expertise a tight 'wait and watch' strategy can be used. Objective: To report on the oncologic results with primary surgical treatment of pT1/pT2 FOMC and to examine the benefit of elective ND in cN0. Methods: This was a retrospective study design including 216 patients who were treated between 1980 and 2010 for pT1/2 FOMC. The 5-year disease-specific survival (DSS), local and (loco)regional control based on the T and N classification and depth of infiltration were investigated. Results: DSS was 79.5% and (loco)regional control was 89.8%. DSS in patients staged pN0 was significantly higher, at 84.6%, than in those staged pN+, at 60%. ND was performed in 165 patients, and adjuvant therapy was administered in 124 patients. Ninety patients (41.7%) were staged cN0, and 53.3% of them underwent elective ND. The risk of occult metastases was 4.8% in pT1 and 28.6% in pT2. A depth of infiltration of ≥ 5 mm showed a markedly higher relative frequency of occult neck metastases and pN+ status. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CHI-squared test
*COMBINED modality therapy
*FISHER exact test
*LYMPH node surgery
*MOUTH tumors
*HEALTH outcome assessment
*MOUTH floor
*PROBABILITY theory
*RADIOTHERAPY
*SQUAMOUS cell carcinoma
*TOMOGRAPHY
*ULTRASONIC imaging
*TREATMENT effectiveness
*RETROSPECTIVE studies
*DATA analysis software
*KAPLAN-Meier estimator
*SURGERY
Subjects
Details
- Language :
- English
- ISSN :
- 00016489
- Volume :
- 133
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Acta Oto-Laryngologica
- Publication Type :
- Academic Journal
- Accession number :
- 89720540
- Full Text :
- https://doi.org/10.3109/00016489.2013.796090