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Targeting tumors with nonreplicating Toxoplasma gondii uracil auxotroph vaccines.

Authors :
Fox, Barbara A.
Sanders, Kiah L.
Chen, Shan
Bzik, David J.
Source :
Trends in Parasitology. Sep2013, Vol. 29 Issue 9, p431-437. 7p.
Publication Year :
2013

Abstract

Highlights: [•] Immunotherapy based on avirulent Toxoplasma reverses tumor-associated immune suppression. [•] Toxoplasma activates tumor-specific CD8+ T cell responses. [•] Toxoplasma immunotherapy regresses established solid tumors. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
14714922
Volume :
29
Issue :
9
Database :
Academic Search Index
Journal :
Trends in Parasitology
Publication Type :
Academic Journal
Accession number :
89885785
Full Text :
https://doi.org/10.1016/j.pt.2013.07.001