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The ne plus ultra for deep BCR-ABL sequencing?

Authors :
Müller, Martin C.
Source :
Blood. 8/29/2013, Vol. 122 Issue 9, p1536-1537. 2p.
Publication Year :
2013

Abstract

The article discusses a study which describes ultra-deep sequencing's (USD) benefits compared with conventional Sanger sequencing in terms of detecting BCR-ABL kinase domain mutations. It reveals that the study could be a help to improve the treatment for resistant patients with chronic myeloid leukemia and acute lymphoblastic leukemia. Information about tyrosine kinase inhibitor (TKI) imatinib is provided.

Details

Language :
English
ISSN :
00064971
Volume :
122
Issue :
9
Database :
Academic Search Index
Journal :
Blood
Publication Type :
Academic Journal
Accession number :
90083349
Full Text :
https://doi.org/10.1182/blood-2013-07-510958