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A small jab – a big effect: nonspecific immunomodulation by vaccines.

Authors :
Benn, Christine S.
Netea, Mihai G.
Selin, Liisa K.
Aaby, Peter
Source :
Trends in Immunology. Sep2013, Vol. 34 Issue 9, p431-439. 9p.
Publication Year :
2013

Abstract

Highlights: [•] Routine vaccines may alter resistance to unrelated pathogens in children. [•] Live vaccines are associated with increased protection to other pathogens. [•] Inactivated vaccines may increase susceptibility to other pathogens. [•] ‘Heterologous immunity’ and ‘trained innate immunity’ may explain these effects. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*IMMUNOREGULATION
*DRUG resistance
*VACCINATION of children
*VACCINES
*PATHOGENIC microorganisms
*DISEASE susceptibility
*NATURAL immunity

Details

Language :
English
ISSN :
14714906
Volume :
34
Issue :
9
Database :
Academic Search Index
Journal :
Trends in Immunology
Publication Type :
Academic Journal
Accession number :
90093852
Full Text :
https://doi.org/10.1016/j.it.2013.04.004
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