Integrative erectile biology: the role of signal transduction and cell-to-cell communication in coordinating corporal smooth muscle tone and penile erection.

Focuses on the role of signal transduction and cell-to-cell communication in coordinating corporal smooth muscle tone and penile erection. Sufficiency of corporal smooth muscle relaxation to elicit a sustained erection; Lack of knowledge on the mechanical physiology of erection; Outline of a cogent explanation for the rapid and syncytial integration of the effects of diverse stimuli in penile smooth muscle cells.