Immune response to 13-valent pneumococcal conjugate vaccine with a reduced dosing schedule.

Highlights: [•] In some routine immunization programs, PCV13 is administered in a 2+1 schedule. [•] Summarized immune responses from 2+1 and 3+1 studies of PCV13 with postdose 2 data. [•] Immune responses to the PCV7 serotypes postdose 2 were similar for PCV13 and PCV7. [•] All 13 serotypes showed boosting posttoddler dose in the 2+1 studies. [•] These results support transition from PCV7 to PCV13 in countries with 2+1 schedules. [ABSTRACT FROM AUTHOR]