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Vaccination with Flt3L-induced CD8α+ dendritic cells prevents CD4+ T helper cell-mediated experimental autoimmune myocarditis.
- Source :
-
Vaccine . Oct2013, Vol. 31 Issue 42, p4802-4811. 10p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Dendritic cell-based vaccination strategy to protect from autoimmune diseases. [•] Flt3L induces maturation of CD8α+ DC. [•] CD8α+ DC vaccination promotes protective CD4+ Th1 cells. [•] Protection conferred by CD8α+ DC vaccination is IFN-γ dependent. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0264410X
- Volume :
- 31
- Issue :
- 42
- Database :
- Academic Search Index
- Journal :
- Vaccine
- Publication Type :
- Academic Journal
- Accession number :
- 90304321
- Full Text :
- https://doi.org/10.1016/j.vaccine.2013.07.084