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IC-4, a new irreversible EGFR inhibitor, exhibits prominent anti-tumor and anti-angiogenesis activities.
- Source :
-
Cancer Letters . Oct2013, Vol. 340 Issue 1, p88-96. 9p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] We reported IC-4 as a novel irreversible TKI for EGFR. [•] IC-4 inhibited proliferation, induced apoptosis and a G2/M arrest in breast cancer cells. [•] IC-4 exhibited anti-angiogenesis effects in vitro and in vivo. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03043835
- Volume :
- 340
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Cancer Letters
- Publication Type :
- Academic Journal
- Accession number :
- 90304426
- Full Text :
- https://doi.org/10.1016/j.canlet.2013.07.005