Back to Search Start Over

Effect of JGK-263 as a new glycogen synthase kinase-3β inhibitor on extrinsic apoptosis pathway in motor neuronal cells.

Authors :
Jeon, Gye Sun
Kim, Jee-Eun
Ahn, Suk-Won
Park, Kyung-Seok
Hong, Yoon-Ho
Ye, In-Hae
Park, Ji-Seon
Kim, Seung Hyun
Lee, Kwang-Woo
Kim, Sung-Min
Sung, Jung-Joon
Source :
Biochemical & Biophysical Research Communications. Sep2013, Vol. 439 Issue 2, p309-314. 6p.
Publication Year :
2013

Abstract

Highlights: [•] JGK-263 can reduce apoptosis by inactivating the intrinsic apoptosis pathway. [•] JGK-263 can reduce apoptosis by inactivating the extrinsic apoptosis pathway. [•] JGK-263 may be effective in preventing motor neuron cell death. [•] JGK-263 has a neuroprotective effect in motor neuron cells. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0006291X
Volume :
439
Issue :
2
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
90390758
Full Text :
https://doi.org/10.1016/j.bbrc.2013.07.080