Unexpected one-pot synthesis of A3-type unsymmetrical porphyrin.

Authors :: Mahmood, Mian HR
Liu, Hai-Yang
Wang, Hua-Hua
Jiang, Yi-Yu
Chang, C.-K.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Oct2013, Vol. 54 Issue 44, p5853-5856. 4p.
Publication Year :: 2013
Abstract: Abstract: The first direct synthesis of A3-type unsymmetrical porphyrin is achieved via conventional pyrrole–aldehyde condensation in a one-pot procedure in an appreciable yield. Generalization of this approach to a variety of other aldehydes revealed that it is advantageous for highly electron-rich aldehydes giving unsymmetrical porphyrin, while electron-poor aldehydes even failed to cyclize under the same experimental conditions. [Copyright &y& Elsevier]

Subjects :: *PORPHYRIN synthesis
*PYRROLES
*ALDEHYDES
*CONDENSATION reactions
*ELECTRONS
*RING formation (Chemistry)

Language :: English
ISSN :: 00404039
Volume :: 54
Issue :: 44
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 90421441
Full Text :: https://doi.org/10.1016/j.tetlet.2013.08.086