Suitability of scoring PCC rings and fragments for dose assessment after high-dose exposures to ionizing radiation.

Authors :: Puig, Roser
Barrios, Leonardo
Pujol, Mònica
Caballín, Maria Rosa
Barquinero, Joan-Francesc
Source :: Mutation Research - Genetic Toxicology & Environmental Mutagenesis. Sep2013, Vol. 757 Issue 1, p1-7. 7p.
Publication Year :: 2013
Abstract: Highlights: [•] The chemical to induce PCC has influence on the dose–effect curve coefficients. [•] Depending on dose, different proportions of PCC in various cell cycle phases were observed. [•] PCC cells in various cell phases show variable yields of chromosome aberrations. [•] CalA induced PCC rings are in general Poisson distributed and useful to discriminate partial body exposure. [ABSTRACT FROM AUTHOR]

Subjects :: *CHROMOSOME abnormalities
*IONIZING radiation dosage
*CELL cycle
*POISSON distribution
*INDECENT exposure
*ENVIRONMENTAL health

Language :: English
ISSN :: 13835718
Volume :: 757
Issue :: 1
Database :: Academic Search Index
Journal :: Mutation Research - Genetic Toxicology & Environmental Mutagenesis
Publication Type :: Academic Journal
Accession number :: 90423037
Full Text :: https://doi.org/10.1016/j.mrgentox.2013.03.013

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