The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin.

Authors :: Eichelbaum, Michel
Greiner, Bernd
Fritz, Peter
Kreichgauer, Hans-Peter
Richter, Oliver von
Zundler, Johannes
Kroemer, Heyo K.
Source :: Journal of Clinical Investigation. 8/15/2002, Vol. 110 Issue 4, p571. 1p.
Publication Year :: 2002
Abstract: Discusses issues related to a study on the role of intestinal P-glycoprotein (P-gp) in the interaction of digoxin and rifampin. Relationship between intestinal P-gp and digoxin bioavailability; Concern regarding the calculation of oral digoxin bioavailability AUC.

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