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IP3 decreases coronary artery tone via activating the BKCa channel of coronary artery smooth muscle cells in pigs.

Authors :
Yang, Yan
Li, Peng-Yun
Cheng, Jun
Cai, Fang
Lei, Ming
Tan, Xiao-Qiu
Li, Miao-Ling
Liu, Zhi-Fei
Zeng, Xiao-Rong
Source :
Biochemical & Biophysical Research Communications. Sep2013, Vol. 439 Issue 3, p363-368. 6p.
Publication Year :
2013

Abstract

Highlights: [•] IP3 activates BKCa channels and exerts a coronary artery-relaxing effect. [•] IP3 enhances the STOC via IP3 receptor. [•] IP3 stimulates the Macro-current by increasing the Ca2+ sensitivity of channels. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0006291X
Volume :
439
Issue :
3
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
90490191
Full Text :
https://doi.org/10.1016/j.bbrc.2013.08.079