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Induction of inflammatory arthropathy resembling rheumatoid arthritis in mice transgenic for HTLV-1.
- Source :
-
Science . 8/30/1991, Vol. 253 Issue 5023, p1026. 3p. 19 Black and White Photographs, 2 Graphs. - Publication Year :
- 1991
-
Abstract
- Explores the pathological role human T cell leukemia virus type-I (HTLV-I) may play in disease. Production of transgenic mice with HTLV-I genome; Development of arthritic condition in mice resembling rheumatoid arthritis; Marked synovial and periarticular inflammation; Possible role of HTLV-I as a etiologic agent of chronic arthritis in humans.
- Subjects :
- *ARTHRITIS
Subjects
Details
- Language :
- English
- ISSN :
- 00368075
- Volume :
- 253
- Issue :
- 5023
- Database :
- Academic Search Index
- Journal :
- Science
- Publication Type :
- Academic Journal
- Accession number :
- 9109233839
- Full Text :
- https://doi.org/10.1126/science.1887217