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Long-lasting changes in the cochlear K+ recycling structures after acute energy failure.

Authors :
Takiguchi, Yoichiro
Sun, Guang-wei
Ogawa, Kaoru
Matsunaga, Tatsuo
Source :
Neuroscience Research. Sep2013, Vol. 77 Issue 1/2, p33-41. 9p.
Publication Year :
2013

Abstract

Highlights: [•] We examined cochlea K+ recycling-related proteins after acute energy failure. [•] Connexin 26 increased and Na,K-ATPase and NKCC1 disappeared in the spiral ligament. [•] Kir4.1 and L-PGDS decreased in the stria vascularis. [•] NKCC1 and connexin 26 were present in the center of the limbus despite nuclei loss. [ • ] Fibrocyte changes may compensate damaged K+ recycling and preserve ATP. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01680102
Volume :
77
Issue :
1/2
Database :
Academic Search Index
Journal :
Neuroscience Research
Publication Type :
Academic Journal
Accession number :
91599464
Full Text :
https://doi.org/10.1016/j.neures.2013.06.003