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Synthetic analogues of bovine bactenecin dodecapeptide reduce herpes simplex virus type 2 infectivity in mice.

Authors :
Shestakov, Andrey
Jenssen, Håvard
Hancock, Robert E.W.
Nordström, Inger
Eriksson, Kristina
Source :
Antiviral Research. Nov2013, Vol. 100 Issue 2, p455-459. 5p.
Publication Year :
2013

Abstract

Highlights: [•] Four synthetic mimics of bovine bactenecin were analyzed for anti-HSV-2 properties. [•] All four peptides blocked viral attachment and entry in vitro. [•] Two peptides, 1018 and HH-2, blocked genital HSV-2 infection in mice when admixed with virus. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
01663542
Volume :
100
Issue :
2
Database :
Academic Search Index
Journal :
Antiviral Research
Publication Type :
Academic Journal
Accession number :
91725066
Full Text :
https://doi.org/10.1016/j.antiviral.2013.08.019