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Paradoxical enhancement of fear expression and extinction deficits in mice resilient to social defeat.

Authors :
Meduri, Jeremy D.
Farnbauch, Laure A.
Jasnow, Aaron M.
Source :
Behavioural Brain Research. Nov2013, Vol. 256, p580-590. 11p.
Publication Year :
2013

Abstract

Highlights: [•] Mice can be characterized as susceptible or resilient after social defeat. [•] Paradoxically, resilient mice display enhanced fear expression and poor extinction. [•] These effects are not due to increased anxiety or poor behavioral flexibility. [•] Mechanisms of resilience may leave animals vulnerable to maladaptive fear behavior. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01664328
Volume :
256
Database :
Academic Search Index
Journal :
Behavioural Brain Research
Publication Type :
Academic Journal
Accession number :
91738490
Full Text :
https://doi.org/10.1016/j.bbr.2013.09.009