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Icaritin opposes the development of social aversion after defeat stress via increases of GR mRNA and BDNF mRNA in mice.

Authors :
Wu, Xiao
Wu, Jinfeng
Xia, Shijin
Li, Bei
Dong, Jingcheng
Source :
Behavioural Brain Research. Nov2013, Vol. 256, p602-608. 7p.
Publication Year :
2013

Abstract

Highlights: [•] Icaritin was a novel antidepressant. [•] It restored social defeat-induced impairment of glucocorticoid sensitivity. [•] These effects are attributed to normalization of the GR function. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01664328
Volume :
256
Database :
Academic Search Index
Journal :
Behavioural Brain Research
Publication Type :
Academic Journal
Accession number :
91738492
Full Text :
https://doi.org/10.1016/j.bbr.2013.09.034