Cells–nano interactions and molecular toxicity after delayed hypersensitivity, in Guinea pigs on exposure to hydroxyapatite nanoparticles.

Highlights: [•] HANP was synthesized by chemical method. [•] Characterized of HANP by TEM, SEM, FT-IR, XRD. [•] The HANPs were biocompatible with more than 80% viable. [•] Non-skin irritant after skin sensitization in G. pigs. [•] Not altered the antioxidant potential in vitro and in vivo. [ABSTRACT FROM AUTHOR]