Back to Search
Start Over
Complexation of two macrocycles for amide, saccharide, and halide derivatives: the capacity of 1,2,3-triazole as hydrogen and halogen bonding acceptors.
- Source :
-
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry . Dec2013, Vol. 54 Issue 50, p6967-6970. 4p. - Publication Year :
- 2013
-
Abstract
- Abstract: Two 1,2,3-triazole- and amide-incorporated macrocycles have been prepared by 1,3-dipolar cycloaddition of the corresponding dialkyne and diazide precursors. Intramolecular C–H⋯O hydrogen bonding is introduced to lock the C5–H atoms of the 1,2,3-triazole rings. The binding of the two macrocycles to amide, monosaccharide, and halide derivatives in chloroform or dichloromethane has been investigated. It is revealed that the amide units dominate their binding toward the amide and monosaccharide guests through forming intermolecular hydrogen bonding and 1,2,3-triazole is as weak as an intermolecular hydrogen bonding acceptor, but it forms intermolecular halogen bonding when cooperative effect exists. [Copyright &y& Elsevier]
- Subjects :
- *MACROCYCLIC compounds
*AMIDES
*SACCHARIDES
*HALIDES
*HYDROGEN bonding
*HALOGENATION
Subjects
Details
- Language :
- English
- ISSN :
- 00404039
- Volume :
- 54
- Issue :
- 50
- Database :
- Academic Search Index
- Journal :
- Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 91847098
- Full Text :
- https://doi.org/10.1016/j.tetlet.2013.10.064