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Development of New Thioester Equivalents for Protein Chemical Synthesis.
- Source :
-
Accounts of Chemical Research . Nov2013, Vol. 46 Issue 11, p2475-2484. 10p. - Publication Year :
- 2013
-
Abstract
- The chemical synthesis of proteins provides synthetic chemists with an interesting challenge and supports biological research through the generation of proteins that are not produced naturally. Although it offers advantages, studies of solid phase peptide synthesis have established limits for this technique: researchers can only prepare peptides up to 50 amino acids in length in sufficient yields and purity. Therefore, researchers have developed techniques to condense peptide segments to build longer polypeptide chains. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00014842
- Volume :
- 46
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Accounts of Chemical Research
- Publication Type :
- Academic Journal
- Accession number :
- 92050952
- Full Text :
- https://doi.org/10.1021/ar400012w