Approved and experimental countermeasures against pestiviral diseases: Bovine viral diarrhea, classical swine fever and border disease.

Highlights: [•] Bovine viral diarrhea, classical swine fever and border disease viruses are major threats to livestock. [•] Control of these pestiviral diseases is difficult due to the presence of persistently infected animals. [•] Antiviral drugs are promising for outbreak control, but few have been field tested. [•] Differentiation of vaccinated from infected animals is currently difficult. [•] Vaccines must protect the fetus against diverse viral strains. [Copyright &y& Elsevier]