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Recombinant duck enteritis virus expressing the HA gene from goose H5 subtype avian influenza virus.

Recombinant duck enteritis virus expressing the HA gene from goose H5 subtype avian influenza virus.

Authors :
Liu, Xiaomei
Wei, Shuangshi
Liu, Yan
Fu, Peifen
Gao, Mingchun
Mu, Xiaoyu
Liu, Hua
Xing, Mingwei
Ma, Bo
Wang, JunWei
Source :
Vaccine. Dec2013, Vol. 31 Issue 50, p5953-5959. 7p.
Publication Year :
2013

Abstract

Highlights: [•] Two recombinant DEVs (rDEV-ΔgIgE and rDEV-ΔUS2) were generated. [•] Two rDEVs expressing the AIV HA (rDEV-ΔgIgE-HA and rDEV-ΔUS2-HA) were generated. [•] The rDEVs and parental DEV were used to immunize four-week-old ducks. [•] The rDEVs immunized ducks induced specific antibodies against DEV and AIV HA. [•] The rDEVs could induce partial protection against a lethal DEV virus challenge. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0264410X
Volume :
31
Issue :
50
Database :
Academic Search Index
Journal :
Vaccine
Publication Type :
Academic Journal
Accession number :
92503143
Full Text :
https://doi.org/10.1016/j.vaccine.2013.10.035