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In vitro generated Th17 cells support the expansion and phenotypic stability of CD4+Foxp3+ regulatory T cells in vivo.
- Source :
-
Cytokine . Jan2014, Vol. 65 Issue 1, p56-64. 9p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] Th17 cells express the highest levels of TNF than other Th subsets. [•] Th17 cells most potently stimulate co-transferred Tregs in Rag1 KO mice. [•] This effect of Th17 cells is TNF- and IL-2-dependent. [•] TNF–TNFR2 plays crucial role in reciprocal stimulation of Th17 cells and Tregs. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 10434666
- Volume :
- 65
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Cytokine
- Publication Type :
- Academic Journal
- Accession number :
- 92591383
- Full Text :
- https://doi.org/10.1016/j.cyto.2013.09.008