Synthesis and characterization of the superparamagnetic iron oxide nanoparticles modified with cationic chitosan and coated with silica shell.

Highlights: [•] The new, facile methodology for synthesis of silica covered SPIONs is proposed. [•] The SPIONs was modified with cationic chitosan and coated with silica shell. [•] Negatively charged, rounded in shape particles of ca. 330nm were obtained. [•] The product exhibits the superparamagnetic properties. [•] The product properties imply its potential applications in biomedicine areas. [ABSTRACT FROM AUTHOR]