ChemInform Abstract: Syntheses and Evaluation of Novel Isoliquiritigenin Derivatives as Potential Dual Inhibitors for Amyloid-Beta Aggregation and 5-Lipoxygenase.

Authors :: Chen, Yi‐Ping
Zhang, Zi‐Ying
Li, Yan‐Ping
Li, Ding
Huang, Shi‐Liang
Gu, Lian‐Quan
Xu, Jun
Huang, Zhi‐Shu
Source :: ChemInform. Dec2013, Vol. 44 Issue 52, pno-no. 1p.
Publication Year :: 2013
Abstract: The compounds (IIIa)-(IIId) show more effective abilities for both title mentioned targets than the reference compounds Resv and ISL. [ABSTRACT FROM AUTHOR]

Subjects :: *CHEMICAL derivatives
*AMYLOID beta-protein
*LIPOXYGENASES
*ENZYME inhibitors
*BENZENE compounds
*OLEFINATION reactions
*RING formation (Chemistry)

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