Back to Search
Start Over
Glimepiride attenuates Aβ production via suppressing BACE1 activity in cortical neurons.
- Source :
-
Neuroscience Letters . Dec2013, Vol. 557 Issue Part B, p90-94. 5p. - Publication Year :
- 2013
-
Abstract
- Highlights: [•] Glimepiride reduces Aβ production in cortical neurons. [•] Glimepiride downregulates expression of BACE1 mRNA and protein. [•] Glimepiride suppresses BACE1 activity. [•] Glimepiride inhibits high glucose-induced Aβ40 production. [•] PPARγ antagonist GW9662 reverses glimepiride inhibition of Aβ40 production. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03043940
- Volume :
- 557
- Issue :
- Part B
- Database :
- Academic Search Index
- Journal :
- Neuroscience Letters
- Publication Type :
- Academic Journal
- Accession number :
- 92743710
- Full Text :
- https://doi.org/10.1016/j.neulet.2013.10.052