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The malian medicinal plant Trichilia emetica; studies on polysaccharides with complement fixing ability
- Source :
-
Journal of Ethnopharmacology . Feb2003, Vol. 84 Issue 2/3, p279. 9p. - Publication Year :
- 2003
-
Abstract
- Trichilia emetica is a tree or bush that has many different traditional uses in Mali, amongst others the leaves have been used as a woundhealing remedy. As polysaccharides have been isolated from other plants that have a long tradition as woundhealing remedies, it was of interest to study the polysaccharides of T. emetica as well. The polysaccharides were extracted at 50 and 100 °C, and the polymeric material was separated into neutral and acidic polymers by anion exchange chromatography. The complement fixation ability of the different fractions was determined. The Acidic fraction 4 of the 100 °C extract was the most active, but most of the other fractions were also quite active. Structural studies showed that the most active fraction was a pectin of the rhamnogalacturonan type 1 with side chains of the arabinogalactan type II. Removal of terminal arabinofuranosides lead to a drop of the activity indicating that this structural unit may be involved in the bioactive site of the molecule. [Copyright &y& Elsevier]
- Subjects :
- *TRICHILIA
*POLYSACCHARIDES
Subjects
Details
- Language :
- English
- ISSN :
- 03788741
- Volume :
- 84
- Issue :
- 2/3
- Database :
- Academic Search Index
- Journal :
- Journal of Ethnopharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 9289996
- Full Text :
- https://doi.org/10.1016/S0378-8741(02)00330-6