A HPLC–MS/MS method for the simultaneous quantitation of six alkaloids of Rhizoma Corydalis Decumbentis in rat plasma and its application to a pharmacokinetic study.

Authors :: Liao, Chuanrong
Chang, Sheng
Yin, Shiliang
Wang, Zhibin
Meng, Yonghai
Source :: Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences. Jan2014, Vol. 944, p101-106. 6p.
Publication Year :: 2014
Abstract: Highlights: [•] The HPLC–MS/MS method was developed for quantification of these six alkaloids in plasma for the first time. [•] Six alkaloids were the major components of Rhizoma Corydalis Decumbentis. [•] The article provided the information about the PK of the six alkaloids in rats. [Copyright &y& Elsevier]

Subjects :: *HIGH performance liquid chromatography
*TANDEM mass spectrometry
*ALKALOIDS
*BLOOD plasma
*PHARMACOKINETICS
*LABORATORY rats

Language :: English
ISSN :: 15700232
Volume :: 944
Database :: Academic Search Index
Journal :: Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences
Publication Type :: Academic Journal
Accession number :: 93347221
Full Text :: https://doi.org/10.1016/j.jchromb.2013.11.010

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