Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation.

In this paper, Choi and colleagues analyzed levels of mitochondrial DNA in two prospective observational cohort studies and found that increased mtDNA levels are associated with ICU mortality, and improve risk prediction in medical ICU patients. The data suggests that mtDNA could serve as a viable plasma biomarker in MICU patients. [ABSTRACT FROM AUTHOR]