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Mitochondrial binding of α-enolase stabilizes mitochondrial membrane: Its role in doxorubicin-induced cardiomyocyte apoptosis.
- Source :
-
Archives of Biochemistry & Biophysics . Jan2014, Vol. 542, p46-55. 10p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] The level of mitochondrial α-enolase decreased during cardiomyocyte apoptosis. [•] Recombinant α-enolase protein specifically stabilized mitochondrial membrane. [•] Loss of mitochondrial α-enolase aggravated Ca2+-induced mitochondrial damage. [•] α-Enolase interacted with voltage dependent anion channels in mitochondrial membrane. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00039861
- Volume :
- 542
- Database :
- Academic Search Index
- Journal :
- Archives of Biochemistry & Biophysics
- Publication Type :
- Academic Journal
- Accession number :
- 93821054
- Full Text :
- https://doi.org/10.1016/j.abb.2013.12.008