Mitochondrial binding of α-enolase stabilizes mitochondrial membrane: Its role in doxorubicin-induced cardiomyocyte apoptosis.

Highlights: [•] The level of mitochondrial α-enolase decreased during cardiomyocyte apoptosis. [•] Recombinant α-enolase protein specifically stabilized mitochondrial membrane. [•] Loss of mitochondrial α-enolase aggravated Ca2+-induced mitochondrial damage. [•] α-Enolase interacted with voltage dependent anion channels in mitochondrial membrane. [ABSTRACT FROM AUTHOR]