Back to Search
Start Over
The extreme N-terminal region of human apolipoprotein A-I has a strong propensity to form amyloid fibrils.
- Source :
-
FEBS Letters . Jan2014, Vol. 588 Issue 3, p389-394. 6p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] The N-terminal 1–83 residues of apoA-I have a propensity to form amyloid fibrils. [•] ApoA-I 1–43 peptide forms amyloid fibrils with transition to β-sheet-rich structure. [•] The G26R point mutation enhances the fibril formation of apoA-I 1–43 peptide. [•] The extreme N-terminal region plays a crucial role in fibril formation by apoA-I. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00145793
- Volume :
- 588
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- FEBS Letters
- Publication Type :
- Academic Journal
- Accession number :
- 94028579
- Full Text :
- https://doi.org/10.1016/j.febslet.2013.11.031