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Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary...

Authors :
Bronner, C. Eric
Baker, Sean M.
Source :
Nature. 3/17/1994, Vol. 368 Issue 6468, p258. 4p. 2 Color Photographs, 2 Diagrams, 4 Graphs.
Publication Year :
1994

Abstract

Proposes the location of the human gene encoding a protein human MutL homolog (hMLH1) on the human chromosome 3p21.3-23. Similarity of the hMLH1 gene product to the yeast DNA mismatch repair protein; Role of the human DNA mismatch repair gene homolog in hereditary non-polyposis colon cancer.

Details

Language :
English
ISSN :
00280836
Volume :
368
Issue :
6468
Database :
Academic Search Index
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
9405181722
Full Text :
https://doi.org/10.1038/368258a0