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Wwp2 targets SRG3, a scaffold protein of the SWI/SNF-like BAF complex, for ubiquitination and degradation.
- Source :
-
Biochemical & Biophysical Research Communications . Jan2014, Vol. 443 Issue 3, p1048-1053. 6p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] Wwp2 and SRG3 form protein complexes in the nucleus in mammalian cells. [•] Wwp2 promotes ubiquitination of SRG3 both in vivo and in vitro. [•] Wwp2 promotes degradation of SRG3 through the ubiquitin-proteasome system. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 443
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 94076258
- Full Text :
- https://doi.org/10.1016/j.bbrc.2013.12.089