A Critical History of Chromic Myeloid Leukemia.

The author reflects on various developments in treatment of chronic myeloid leukemia (CML), a cancer of white blood cells (WBCs). Topics discussed include development of targeted treatments for CML such as by targeting the tyrosine kinase inhibitors (TKIs), history of treatment of CML such as by using chemotherapy, radiation, and allogeneic stem cell transplantation (SCT), and development of several TKI such as imatinib, a medicine, which target BCR-ABL1 activity of the kinase.