Identifying directional persistence in intracellular particle motion using Hidden Markov Models.

Highlights: [•] We study directional persistence in intracellular particle motion. [•] We use a Hidden Markov Model to describe active/non-active switching behavior. [•] A multi-scale turning angle model describes directional persistence. [•] Reference data with inhibited activation is used as calibration. [•] Experiments on microtubule transport and myosin activation gives good results. [ABSTRACT FROM AUTHOR]