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The behavioral, pathological and therapeutic features of the senescence-accelerated mouse prone 8 strain as an Alzheimer's disease animal model.
- Source :
-
Ageing Research Reviews . Jan2014, Vol. 13, p13-37. 25p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] This review focuses on the behavioral and histopathological signature of AD in SAMP8 mice. [•] The behavioral and pathological features detected by the different methods in SAMP8 mice at different ages were listed. [•] The preclinical trials of potential therapeutic modalities using SAMP8 mice were summarized. [•] We compared the merits and limitations of SAMP8 mice with the transgenic mouse as AD animal model. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15681637
- Volume :
- 13
- Database :
- Academic Search Index
- Journal :
- Ageing Research Reviews
- Publication Type :
- Academic Journal
- Accession number :
- 94407221
- Full Text :
- https://doi.org/10.1016/j.arr.2013.10.002